| |
|
|
Home Page > Instrumentation
 |
Request Information
[ Online Brochure]
Watch Video
|
|
Product Description
Model 400
The Model 400 is designed to prepare pharmaceutical peptides consistently and efficiently on production. The Model 400 can utilize standard Boc or Fmoc protocols, or the user can develop custom protocols to optimize product purity and synthesis yield. Reagents and amino acids are accurately and precisely dispensed through separate measuring vessels equipped with adjustable liquid sensors. The amino acids are preactivated in a preactivation vessel before transfer to the reaction vessel; this eliminates side reactions between the resin-peptide and coupling reagents and produces a purer peptide product. Thorough, efficient mixing in the reaction vessel is obtained by nitrogen bubbling and/or orbital shaking.
The Model 400 is available in multiple configurations suitable for small (20 g - 100g resin-peptide), medium (100g 3 kg resin-peptide), or large scale (over 3 kg of resin-peptide) production. AAPPTec will custom build the Model 400 to your specifications.
FDA Compliant
- Optional 21CFR11 module for companies implementing digital record-keeping
- Reactants, reagents and solvents contact only inert materials
- Key-lock access for cabinets
- Encrypted password access for each user
- Battery system in case of power outage
- Failure detection with corrective action
- Leak detection and alarms
- Error correcting protocol ensures data validity
- Stainless steel cabinets for easy cleaning
Separated Systems to Minimize Potential Cross Contamination
- Solvent delivery
- Reagent delivery
- Pre-activation
- Reaction and mixing
- Deprotection
- Waste handling and segregation
|
|